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TABLE 5

MRI results in diabetic patients and control subjects

MRI ratingsControl subjects (n = 36)Type 1 diabetic patients (n = 37)Mean dif (95% CI)
PWML 6.0 (5.0–6.0) 6.0 (6.0–7.0) 0.5 (−0.5 to 1.0) 
DWML 4.0 (2.5–6.0) 3.0 (1.5–6.0) −1.0 (−3.0 to 1.5) 
Cortical atrophy    
    FFR (*10) 0.30 ± 0.10 0.33 ± 0.12 0.01 (−0.04 to 0.06) 
    SFR (*10) 0.31 ± 0.08 0.33 ± 0.10 0.01 (−0.03 to 0.06) 
Subcortical atrophy    
    BCR 0.12 ± 0.03 0.14 ± 0.03 0.01 (−0.01 to 0.02) 
    BFR 0.31 ± 0.05 0.33 ± 0.04 0.01 (−0.01 to 0.03) 
   OR (95% CI) 
(Silent) infarct 8% 8% 1.01 (0.16–6.23) 
MRI ratingsControl subjects (n = 36)Type 1 diabetic patients (n = 37)Mean dif (95% CI)
PWML 6.0 (5.0–6.0) 6.0 (6.0–7.0) 0.5 (−0.5 to 1.0) 
DWML 4.0 (2.5–6.0) 3.0 (1.5–6.0) −1.0 (−3.0 to 1.5) 
Cortical atrophy    
    FFR (*10) 0.30 ± 0.10 0.33 ± 0.12 0.01 (−0.04 to 0.06) 
    SFR (*10) 0.31 ± 0.08 0.33 ± 0.10 0.01 (−0.03 to 0.06) 
Subcortical atrophy    
    BCR 0.12 ± 0.03 0.14 ± 0.03 0.01 (−0.01 to 0.02) 
    BFR 0.31 ± 0.05 0.33 ± 0.04 0.01 (−0.01 to 0.03) 
   OR (95% CI) 
(Silent) infarct 8% 8% 1.01 (0.16–6.23) 

Data are given as unadjusted means ± SD or median (interquartile range) unless otherwise indicated. Mean dif: the adjusted between group difference (type 1 diabetic patients − control subjects) in the univariate ANOVA. Mean difference and OR were adjusted for estimated premorbid IQ and sex. FFR, frontal interhemispheric fissure ratio; SFR, Sylvian fissure ratio.

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