Clinical characteristics of the study subjects
| Parameters . | Normal subjects . | MONW subjects . |
|---|---|---|
| n | 20 | 20 |
| Age (years) | 33.1 ± 1.6 | 34.3 ± 1.5 |
| Sex (male/female) | 19/1 | 19/1 |
| BMI (kg/m2) | 21.0 ± 0.3 | 23.5 ± 0.2† |
| Body fat weight (kg) | 11.8 ± 0.6 | 17.1 ± 0.5† |
| Visceral fat area (cm2) | 57.5 ± 5.5 | 134.4 ± 5.1† |
| Subcutaneous fat area (cm2) | 97.9 ± 7.4 | 157.5 ± 15.2† |
| Fasting plasma glucose (mmol/l) | 4.9 ± 0.3 | 5.0 ± 0.1 |
| Glucose AUC (mmol/l) | 749.8 ± 25.0 | 812.1 ± 27.6 |
| Fasting serum insulin (pmol/l) | 26.4 ± 1.6 | 49.8 ± 6.0† |
| Insulin AUC (pmol/l) | 33,542.7 ± 3,213.1 | 46,438.2 ± 5,011.2* |
| ΔI30/ΔG30 | 124.3 ± 10.8 | 162.7 ± 31.3 |
| Total cholesterol (mmol/l) | 4.31 ± 0.20 | 4.37 ± 0.21 |
| TG (mmol/l) | 1.05 ± 0.07 | 1.89 ± 0.23† |
| HDL cholesterol (mmol/l) | 1.31 ± 0.06 | 1.21 ± 0.04 |
| Serum free fatty acid (mmol/l) | 0.46 ± 0.05 | 0.47 ± 0.04 |
| Systolic blood pressure (mmHg) | 116.2 ± 2.3 | 127.4 ± 2.2† |
| Diastolic blood pressure (mmHg) | 71.7 ± 2.1 | 80.0 ± 1.3† |
| GIR (μmol · kg−1 · min−1) | 60.2 ± 2.9 | 45.4 ± 1.4† |
| Parameters . | Normal subjects . | MONW subjects . |
|---|---|---|
| n | 20 | 20 |
| Age (years) | 33.1 ± 1.6 | 34.3 ± 1.5 |
| Sex (male/female) | 19/1 | 19/1 |
| BMI (kg/m2) | 21.0 ± 0.3 | 23.5 ± 0.2† |
| Body fat weight (kg) | 11.8 ± 0.6 | 17.1 ± 0.5† |
| Visceral fat area (cm2) | 57.5 ± 5.5 | 134.4 ± 5.1† |
| Subcutaneous fat area (cm2) | 97.9 ± 7.4 | 157.5 ± 15.2† |
| Fasting plasma glucose (mmol/l) | 4.9 ± 0.3 | 5.0 ± 0.1 |
| Glucose AUC (mmol/l) | 749.8 ± 25.0 | 812.1 ± 27.6 |
| Fasting serum insulin (pmol/l) | 26.4 ± 1.6 | 49.8 ± 6.0† |
| Insulin AUC (pmol/l) | 33,542.7 ± 3,213.1 | 46,438.2 ± 5,011.2* |
| ΔI30/ΔG30 | 124.3 ± 10.8 | 162.7 ± 31.3 |
| Total cholesterol (mmol/l) | 4.31 ± 0.20 | 4.37 ± 0.21 |
| TG (mmol/l) | 1.05 ± 0.07 | 1.89 ± 0.23† |
| HDL cholesterol (mmol/l) | 1.31 ± 0.06 | 1.21 ± 0.04 |
| Serum free fatty acid (mmol/l) | 0.46 ± 0.05 | 0.47 ± 0.04 |
| Systolic blood pressure (mmHg) | 116.2 ± 2.3 | 127.4 ± 2.2† |
| Diastolic blood pressure (mmHg) | 71.7 ± 2.1 | 80.0 ± 1.3† |
| GIR (μmol · kg−1 · min−1) | 60.2 ± 2.9 | 45.4 ± 1.4† |
Data are means ± SE.
P < 0.05;
P < 0.01 vs. normal subjects.