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Table 1—

Clinical characteristics of the study subjects

ParametersNormal subjectsMONW subjects
n 20 20 
Age (years) 33.1 ± 1.6 34.3 ± 1.5 
Sex (male/female) 19/1 19/1 
BMI (kg/m221.0 ± 0.3 23.5 ± 0.2 
Body fat weight (kg) 11.8 ± 0.6 17.1 ± 0.5 
Visceral fat area (cm257.5 ± 5.5 134.4 ± 5.1 
Subcutaneous fat area (cm297.9 ± 7.4 157.5 ± 15.2 
Fasting plasma glucose (mmol/l) 4.9 ± 0.3 5.0 ± 0.1 
Glucose AUC (mmol/l) 749.8 ± 25.0 812.1 ± 27.6 
Fasting serum insulin (pmol/l) 26.4 ± 1.6 49.8 ± 6.0 
Insulin AUC (pmol/l) 33,542.7 ± 3,213.1 46,438.2 ± 5,011.2* 
ΔI30/ΔG30 124.3 ± 10.8 162.7 ± 31.3 
Total cholesterol (mmol/l) 4.31 ± 0.20 4.37 ± 0.21 
TG (mmol/l) 1.05 ± 0.07 1.89 ± 0.23 
HDL cholesterol (mmol/l) 1.31 ± 0.06 1.21 ± 0.04 
Serum free fatty acid (mmol/l) 0.46 ± 0.05 0.47 ± 0.04 
Systolic blood pressure (mmHg) 116.2 ± 2.3 127.4 ± 2.2 
Diastolic blood pressure (mmHg) 71.7 ± 2.1 80.0 ± 1.3 
GIR (μmol · kg−1 · min−160.2 ± 2.9 45.4 ± 1.4 
ParametersNormal subjectsMONW subjects
n 20 20 
Age (years) 33.1 ± 1.6 34.3 ± 1.5 
Sex (male/female) 19/1 19/1 
BMI (kg/m221.0 ± 0.3 23.5 ± 0.2 
Body fat weight (kg) 11.8 ± 0.6 17.1 ± 0.5 
Visceral fat area (cm257.5 ± 5.5 134.4 ± 5.1 
Subcutaneous fat area (cm297.9 ± 7.4 157.5 ± 15.2 
Fasting plasma glucose (mmol/l) 4.9 ± 0.3 5.0 ± 0.1 
Glucose AUC (mmol/l) 749.8 ± 25.0 812.1 ± 27.6 
Fasting serum insulin (pmol/l) 26.4 ± 1.6 49.8 ± 6.0 
Insulin AUC (pmol/l) 33,542.7 ± 3,213.1 46,438.2 ± 5,011.2* 
ΔI30/ΔG30 124.3 ± 10.8 162.7 ± 31.3 
Total cholesterol (mmol/l) 4.31 ± 0.20 4.37 ± 0.21 
TG (mmol/l) 1.05 ± 0.07 1.89 ± 0.23 
HDL cholesterol (mmol/l) 1.31 ± 0.06 1.21 ± 0.04 
Serum free fatty acid (mmol/l) 0.46 ± 0.05 0.47 ± 0.04 
Systolic blood pressure (mmHg) 116.2 ± 2.3 127.4 ± 2.2 
Diastolic blood pressure (mmHg) 71.7 ± 2.1 80.0 ± 1.3 
GIR (μmol · kg−1 · min−160.2 ± 2.9 45.4 ± 1.4 

Data are means ± SE.

*

P < 0.05;

P < 0.01 vs. normal subjects.

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