Table 1—

Demographic, behavioral, and physiological characteristics of 11,615 adults ages 48–67 years without type 2 diabetes by quartile of depressive symptoms

CovariateQuartile of depressive symptoms
P values for trend*
Quartile 1Quartile 2Quartile 3Quartile 4
 1.20 (0–3) 5.84 (4–8) 11.5 (9–14) 22.2 (15–42)  
n 2,782 3,468 2,525 2,840  
Age (years) 56.4 ± 5.59 56.7 ± 5.68 56.9 ± 5.71 57.0 ± 5.81 <0.01 
African American (%) 15.2 20.1 23.6 27.1 <0.001 
Female (%) 39.6 51.3 61.8 70.1 <0.001 
High school education or less (%) 41.5 48.5 55.8 65.5 <0.001 
Anti-depressant medication use (%) 0.3 0.6 1.5 3.2 <0.001 
Physical activity score 2.69 ± 0.83 2.52 ± 0.81 2.42 ± 0.77 2.26 ± 0.73 <0.01 
Caloric intake (kcal/day) 1,595 ± 630 1,620 ± 677 1,640 ± 679 1,677 ± 713 <0.01 
Current smokers (%) 18.4 19.8 25.3 28.0 <0.001 
Fasting insulin (pmol/l) 70.9 ± 52 73.9 ± 57 74.6 ± 53 79.2 ± 62 <0.01 
Fasting glucose (mmol/l) 5.63 ± 0.52 5.64 ± 0.51 5.63 ± 0.51 5.63 ± 0.54 0.53 
BMI (kg/m226.8 ± 4.3 27.2 ± 4.8 27.4 ± 5.2 28.2 ± 5.9 <0.01 
Waist-to-hip ratio 0.92 ± 0.08 0.92 ± 0.08 0.91 ± 0.08 0.92 ± 0.08 0.30 
Triglycerides (mmol/l) 1.42 ± 0.79 1.42 ± 0.90 1.44 ± 0.82 1.49 ± 0.91 <0.01 
HDL cholesterol (mmol/l) 1.26 ± 0.41 1.31 ± 0.44 1.34 ± 0.45 1.34 ± 0.44 <0.01 
Systolic blood pressure (mmHg) 119 ± 17 120 ± 18 120 ± 19 121 ± 20 <0.01 
CovariateQuartile of depressive symptoms
P values for trend*
Quartile 1Quartile 2Quartile 3Quartile 4
 1.20 (0–3) 5.84 (4–8) 11.5 (9–14) 22.2 (15–42)  
n 2,782 3,468 2,525 2,840  
Age (years) 56.4 ± 5.59 56.7 ± 5.68 56.9 ± 5.71 57.0 ± 5.81 <0.01 
African American (%) 15.2 20.1 23.6 27.1 <0.001 
Female (%) 39.6 51.3 61.8 70.1 <0.001 
High school education or less (%) 41.5 48.5 55.8 65.5 <0.001 
Anti-depressant medication use (%) 0.3 0.6 1.5 3.2 <0.001 
Physical activity score 2.69 ± 0.83 2.52 ± 0.81 2.42 ± 0.77 2.26 ± 0.73 <0.01 
Caloric intake (kcal/day) 1,595 ± 630 1,620 ± 677 1,640 ± 679 1,677 ± 713 <0.01 
Current smokers (%) 18.4 19.8 25.3 28.0 <0.001 
Fasting insulin (pmol/l) 70.9 ± 52 73.9 ± 57 74.6 ± 53 79.2 ± 62 <0.01 
Fasting glucose (mmol/l) 5.63 ± 0.52 5.64 ± 0.51 5.63 ± 0.51 5.63 ± 0.54 0.53 
BMI (kg/m226.8 ± 4.3 27.2 ± 4.8 27.4 ± 5.2 28.2 ± 5.9 <0.01 
Waist-to-hip ratio 0.92 ± 0.08 0.92 ± 0.08 0.91 ± 0.08 0.92 ± 0.08 0.30 
Triglycerides (mmol/l) 1.42 ± 0.79 1.42 ± 0.90 1.44 ± 0.82 1.49 ± 0.91 <0.01 
HDL cholesterol (mmol/l) 1.26 ± 0.41 1.31 ± 0.44 1.34 ± 0.45 1.34 ± 0.44 <0.01 
Systolic blood pressure (mmHg) 119 ± 17 120 ± 18 120 ± 19 121 ± 20 <0.01 

Data are means (range) and mean ± SD for continuous variables and percentage of individuals with a given characteristic for categorical variables.

*

For continuous variables, P value is from trend test; for categorical variables, P value is from χ2 test.

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