RH of type 2 diabetes over 6 years of follow-up by vital exhaustion depression subscore among 11,615 individuals age 48–67 years
| Vital exhaustion depression subscore category* . | Age, race, ARIC center, education, and sex adjusted hazard ratio (95% CI)† . | Fully adjusted model (95% CI)‡ . |
|---|---|---|
| Vegetative score | 1.22 (1.11–1.36)§ | 1.10 (0.99–1.23) |
| Nonvegetative score | 1.20 (1.09–1.32)§ | 1.09 (0.98–1.20) |
| Functional score | 1.23 (1.11–1.36)§ | 1.11 (1.00–1.23)§ |
| Vital exhaustion depression subscore category* . | Age, race, ARIC center, education, and sex adjusted hazard ratio (95% CI)† . | Fully adjusted model (95% CI)‡ . |
|---|---|---|
| Vegetative score | 1.22 (1.11–1.36)§ | 1.10 (0.99–1.23) |
| Nonvegetative score | 1.20 (1.09–1.32)§ | 1.09 (0.98–1.20) |
| Functional score | 1.23 (1.11–1.36)§ | 1.11 (1.00–1.23)§ |
Vegetative symptoms (fatigue, sleep pattern, energy, concentration); nonvegetative symptoms (crying spells, hopelessness, irritability, enjoyment of sex, suicidality); functional symptoms (coping, productivity).
Risk of incident type 2 diabetes per interquartile range increase in vital exhaustion depression subscore category (each hazard ratio has been standardized to the interquartile range for the distribution of its scores).
Adjusted for age, race, ARIC center, education, sex, fasting insulin, fasting glucose, log triglycerides, HDL cholesterol, BMI, waist-to-hip ratio, systolic blood pressure, physical activity, total caloric intake, and smoking status.
P < 0.05.