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Table 1—

Baseline characteristics of the EURODLAB PCS population

nTotal CHD+Total CHDMen CHD+Men CHDWomen CHD+Women CHD
n  151 2,178 69 1,133 82 1,045 
Age (years) 2,329 38.1 ± 10.5 31.7 ± 9.5 37.4 ± 10.5 31.8 ± 9.5 38.6 ± 10.6 31.6 ± 9.5 
Diabetes duration (years) 2,328 19.0 ± 10.3 14.0 ± 8.8 17.9 ± 10.5 13.7 ± 8.7 19.9 ± 10.1 14.3 ± 9.0 
GHb (%) 2,313 6.85 ± 1.63 6.63 ± 1.88 6.98 ± 1.65 6.57 ± 1.84 6.74 ± 1.61 6.69 ± 1.91 
Systolic BP (mmHg) 2,321 126.9 ± 19.9 119.7 ± 16.5 127.6 ± 21.4 122.4 ± 16.0 126.2 ± 18.7 116.8 ± 16.5 
Diastolic BP (mmHg) 2,321 75.0 ± 11.8 75.0 ± 11.2 75.8 ± 12.3 76.2 ± 11.2 74.4 ± 11.3 73.7 ± 11.0 
Cholesterol (mg/dl) 2,303 214.2 ± 46.3 204.8 ± 43.3 208.4 ± 47.4 200.0 ± 42.6 219.2 ± 45.1 210.1 ± 43.4 
LDL cholesterol (mg/dl) 1,545 136.0 ± 41.9 128.2 ± 37.4 136.1 ± 44.0 127.0 ± 36.6 136.8 ± 40.9 129.8 ± 38.9 
HDL cholesterol (mg/dl) 2,288 56.2 ± 17.0 58.2 ± 16.5 50.7 ± 13.9 53.6 ± 14.9 61.0 ± 18.1 63.2 ± 16.8 
Non-HDL cholesterol (mg/dl) 2,288 158.0 ± 47.4 146.6 ± 43.8 157.6 ± 49.6 146.3 ± 43.0 158.2 ± 45.8 146.8 ± 44.7 
FTG (mg/dl) 1,565 93.8 (65.2–135.7) 79.5 (60.7–110.7) 100.4 (69.2–143.3) 83.0 (62.5–118.8) 85.7 (63.4–133.0) 76.8 (58.9–100.0) 
Waist circumference (cm) 2,318 81.6 ± 10.1 79.4 ± 9.4 86.6 ± 8.5 83.2 ± 8.7 77.4 ± 9.4 75.3 ± 8.5 
WHR 2,318 0.86 ± 0.10 0.84 ± 0.10 0.92 ± 0.07 0.88 ± 0.08 0.82 ± 0.10 0.80 ± 0.10 
BMI (kg/m22,312 23.9 ± 2.9 23.5 ± 2.8 24.3 ± 2.8 23.6 ± 2.6 23.6 ± 3.0 23.3 ± 2.9 
AER (μg/min) 2,225 20.2 (8.6–87.9) 10.7 (6.5–21.9) 35.9 (9.1–278.2) 11.3 (6.8–25.4) 15.7 (8.5–81.4) 10.1 (6.2–19.8) 
Insulin dose (units • day−1 • kg−12,290 0.64 (0.53–0.77) 0.67 (0.54–0.81) 0.67 (0.53–0.79) 0.66 (0.54–0.81) 0.62 (0.53–0.76) 0.67 (0.55–0.82) 
No. of insulin injections/day 2,325 2.37 ± 0.68 2.58 ± 0.75 2.32 ± 0.74 2.54 ± 0.74 2.41 ± 0.63 2.62 ± 0.76 
Hypertension (yes) 2,329 34 (51) 21 (450) 35 (24) 23 (256) 33 (27) 19 (194) 
BP-lowering drugs (yes) 2,316 18 (27) 7.5 (162) 20 (14) 7.7 (87) 16 (13) 7.2 (75) 
Lipid-lowering drugs (yes) 2,322 2.7 (4) 1.2 (27) 4 (3) 1.4 (16) 1.2 (1) 1.1 (11) 
Current smoking 2,322 35 (52) 31 (667) 43 (30) 33 (369) 27 (22) 29 (298) 
Exsmoking 2,322 17 (25) 18 (389) 22 (15) 21 (242) 12 (10) 14 (147) 
Retinopathy* 1,919 64 (74) 44 (790) 62 (36) 46 (435) 67 (38) 41 (355) 
Neuropathy 2,284 46 (69) 31 (653) 51 (35) 31 (343) 41 (34) 30 (310) 
Autonomic neuropathy 2,162 38 (53) 28 (557) 43 (27) 27 (277) 35 (26) 29 (280) 
Microalbuminuria 2,225 31 (44) 20 (427) 33 (20) 22 (241) 30 (24) 19 (186) 
Macroalbuminuria 2,225 19 (27) 7.0 (145) 26 (16) 7.7 (83) 14 (11) 6 (62) 
nTotal CHD+Total CHDMen CHD+Men CHDWomen CHD+Women CHD
n  151 2,178 69 1,133 82 1,045 
Age (years) 2,329 38.1 ± 10.5 31.7 ± 9.5 37.4 ± 10.5 31.8 ± 9.5 38.6 ± 10.6 31.6 ± 9.5 
Diabetes duration (years) 2,328 19.0 ± 10.3 14.0 ± 8.8 17.9 ± 10.5 13.7 ± 8.7 19.9 ± 10.1 14.3 ± 9.0 
GHb (%) 2,313 6.85 ± 1.63 6.63 ± 1.88 6.98 ± 1.65 6.57 ± 1.84 6.74 ± 1.61 6.69 ± 1.91 
Systolic BP (mmHg) 2,321 126.9 ± 19.9 119.7 ± 16.5 127.6 ± 21.4 122.4 ± 16.0 126.2 ± 18.7 116.8 ± 16.5 
Diastolic BP (mmHg) 2,321 75.0 ± 11.8 75.0 ± 11.2 75.8 ± 12.3 76.2 ± 11.2 74.4 ± 11.3 73.7 ± 11.0 
Cholesterol (mg/dl) 2,303 214.2 ± 46.3 204.8 ± 43.3 208.4 ± 47.4 200.0 ± 42.6 219.2 ± 45.1 210.1 ± 43.4 
LDL cholesterol (mg/dl) 1,545 136.0 ± 41.9 128.2 ± 37.4 136.1 ± 44.0 127.0 ± 36.6 136.8 ± 40.9 129.8 ± 38.9 
HDL cholesterol (mg/dl) 2,288 56.2 ± 17.0 58.2 ± 16.5 50.7 ± 13.9 53.6 ± 14.9 61.0 ± 18.1 63.2 ± 16.8 
Non-HDL cholesterol (mg/dl) 2,288 158.0 ± 47.4 146.6 ± 43.8 157.6 ± 49.6 146.3 ± 43.0 158.2 ± 45.8 146.8 ± 44.7 
FTG (mg/dl) 1,565 93.8 (65.2–135.7) 79.5 (60.7–110.7) 100.4 (69.2–143.3) 83.0 (62.5–118.8) 85.7 (63.4–133.0) 76.8 (58.9–100.0) 
Waist circumference (cm) 2,318 81.6 ± 10.1 79.4 ± 9.4 86.6 ± 8.5 83.2 ± 8.7 77.4 ± 9.4 75.3 ± 8.5 
WHR 2,318 0.86 ± 0.10 0.84 ± 0.10 0.92 ± 0.07 0.88 ± 0.08 0.82 ± 0.10 0.80 ± 0.10 
BMI (kg/m22,312 23.9 ± 2.9 23.5 ± 2.8 24.3 ± 2.8 23.6 ± 2.6 23.6 ± 3.0 23.3 ± 2.9 
AER (μg/min) 2,225 20.2 (8.6–87.9) 10.7 (6.5–21.9) 35.9 (9.1–278.2) 11.3 (6.8–25.4) 15.7 (8.5–81.4) 10.1 (6.2–19.8) 
Insulin dose (units • day−1 • kg−12,290 0.64 (0.53–0.77) 0.67 (0.54–0.81) 0.67 (0.53–0.79) 0.66 (0.54–0.81) 0.62 (0.53–0.76) 0.67 (0.55–0.82) 
No. of insulin injections/day 2,325 2.37 ± 0.68 2.58 ± 0.75 2.32 ± 0.74 2.54 ± 0.74 2.41 ± 0.63 2.62 ± 0.76 
Hypertension (yes) 2,329 34 (51) 21 (450) 35 (24) 23 (256) 33 (27) 19 (194) 
BP-lowering drugs (yes) 2,316 18 (27) 7.5 (162) 20 (14) 7.7 (87) 16 (13) 7.2 (75) 
Lipid-lowering drugs (yes) 2,322 2.7 (4) 1.2 (27) 4 (3) 1.4 (16) 1.2 (1) 1.1 (11) 
Current smoking 2,322 35 (52) 31 (667) 43 (30) 33 (369) 27 (22) 29 (298) 
Exsmoking 2,322 17 (25) 18 (389) 22 (15) 21 (242) 12 (10) 14 (147) 
Retinopathy* 1,919 64 (74) 44 (790) 62 (36) 46 (435) 67 (38) 41 (355) 
Neuropathy 2,284 46 (69) 31 (653) 51 (35) 31 (343) 41 (34) 30 (310) 
Autonomic neuropathy 2,162 38 (53) 28 (557) 43 (27) 27 (277) 35 (26) 29 (280) 
Microalbuminuria 2,225 31 (44) 20 (427) 33 (20) 22 (241) 30 (24) 19 (186) 
Macroalbuminuria 2,225 19 (27) 7.0 (145) 26 (16) 7.7 (83) 14 (11) 6 (62) 

Data are means ± SD, median (interquartile range), or % (n).

*

Nonproliferative and proliferative retinopathy.

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