TABLE 3

Influence of background retinopathy and premorbid intellectual ability (NART) on neuropsychological performance

Neuropsychological domainNo retinopathyRetinopathyNo retinopathy (Z score)Retinopathy (Z score)Effect of retinopathyEffect of NART
Performance IQ (WAIS-R scaled scores) 43.1 ± 8.0 37.6 ± 8.2 0.22 −0.41 P = 0.008, Eta2 = 0.14 P < 0.0001, Eta2 = 0.32 
 Picture completion 9.4 ± 2.9 8.5 ± 2.4 0.07 −0.13 P = 0.39, Eta2 = 0.01  
 Block design 12.3 ± 2.5 9.7 ± 3.3 0.32 −0.55 P < 0.001, Eta2 = 0.22  
 Object assembly 10.0 ± 3.0 9.2 ± 2.3 0.07 −0.13 P = 0.44, Eta2 = 0.01  
 Digit symbol substitution 11.4 ± 2.5 10.2 ± 2.5 0.19 −0.28 P = 0.04, Eta2 = 0.07  
Frontal and executive functions       
 Verbal fluency score 43.3 ± 13.0 46.4 ± 11.7 −0.04 0.07 P = 0.72, Eta2 < 0.01 P = 0.01, Eta2 = 0.13 
Information processing       
 Inspection time (ms) 46.8 ± 17.9 56.2 ± 17.5 −0.15 0.29 P = 0.03, Eta2 = 0.09 P = 0.78, Eta2 < 0.01 
 Median four-choice reaction time (ms) 308.2 ± 43.1 346.2 ± 60.2 −0.23 0.44 P = 0.003, Eta2 = 0.17 P = 0.13, Eta2 = 0.05 
Attention and concentration       
 PASAT 2s errors 23.3 ± 10.1 28.0 ± 14.2 −0.16 0.30 P = 0.03, Eta2 = 0.09 P = 0.009, Eta2 = 0.14 
Neuropsychological domainNo retinopathyRetinopathyNo retinopathy (Z score)Retinopathy (Z score)Effect of retinopathyEffect of NART
Performance IQ (WAIS-R scaled scores) 43.1 ± 8.0 37.6 ± 8.2 0.22 −0.41 P = 0.008, Eta2 = 0.14 P < 0.0001, Eta2 = 0.32 
 Picture completion 9.4 ± 2.9 8.5 ± 2.4 0.07 −0.13 P = 0.39, Eta2 = 0.01  
 Block design 12.3 ± 2.5 9.7 ± 3.3 0.32 −0.55 P < 0.001, Eta2 = 0.22  
 Object assembly 10.0 ± 3.0 9.2 ± 2.3 0.07 −0.13 P = 0.44, Eta2 = 0.01  
 Digit symbol substitution 11.4 ± 2.5 10.2 ± 2.5 0.19 −0.28 P = 0.04, Eta2 = 0.07  
Frontal and executive functions       
 Verbal fluency score 43.3 ± 13.0 46.4 ± 11.7 −0.04 0.07 P = 0.72, Eta2 < 0.01 P = 0.01, Eta2 = 0.13 
Information processing       
 Inspection time (ms) 46.8 ± 17.9 56.2 ± 17.5 −0.15 0.29 P = 0.03, Eta2 = 0.09 P = 0.78, Eta2 < 0.01 
 Median four-choice reaction time (ms) 308.2 ± 43.1 346.2 ± 60.2 −0.23 0.44 P = 0.003, Eta2 = 0.17 P = 0.13, Eta2 = 0.05 
Attention and concentration       
 PASAT 2s errors 23.3 ± 10.1 28.0 ± 14.2 −0.16 0.30 P = 0.03, Eta2 = 0.09 P = 0.009, Eta2 = 0.14 

Data are means ± SD, unless otherwise indicated.

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