TABLE 1

Frequency of diabetes and birth weight by −23 Hph1 genotype

A/AA/TT/TTotal
n (%)     
 Offspring + both parents 458 (69.4) 179 (27.2) 23 (3.5) 660 
 Offspring only 293 (70.1) 113 (27.0) 12 (2.9) 418 
Sex (M/F)     
 Offspring + both parents 212/245 72/117 13/10 660 
 Offspring only 126/167 45/68 7/5 418 
Number with diabetes (%)     
 Offspring + both parents 255 (55.6) 115 (64.3) 16 (69.6) 386 
 Offspring only 140 (47.8) 59 (52.2) 6 (50) 205 
Age of diabetes onset (years)     
 Offspring + both parents 33.7 ± 11.8 33.3 ± 12.1 31.4 ± 8.3 386 
 Offspring only 28.1 ± 9.1 26.9 ± 9.8 29.1 ± 9.8 205 
Age at last exam (years)     
 Offspring + both parents 40.9 ± 15.6 39.4 ± 16.5 36.6 ± 14.3 660 
 Offspring only 32.9 ± 10.6 30.1 ± 11.0 28.7 ± 13.2 418 
Birth weight*     
n (%) 133 (69.3) 54 (28.1) 5 (2.6) 192 
 kg 3.73 ± 0.48 3.64 ± 0.52 3.62 ± 0.50  
A/AA/TT/TTotal
n (%)     
 Offspring + both parents 458 (69.4) 179 (27.2) 23 (3.5) 660 
 Offspring only 293 (70.1) 113 (27.0) 12 (2.9) 418 
Sex (M/F)     
 Offspring + both parents 212/245 72/117 13/10 660 
 Offspring only 126/167 45/68 7/5 418 
Number with diabetes (%)     
 Offspring + both parents 255 (55.6) 115 (64.3) 16 (69.6) 386 
 Offspring only 140 (47.8) 59 (52.2) 6 (50) 205 
Age of diabetes onset (years)     
 Offspring + both parents 33.7 ± 11.8 33.3 ± 12.1 31.4 ± 8.3 386 
 Offspring only 28.1 ± 9.1 26.9 ± 9.8 29.1 ± 9.8 205 
Age at last exam (years)     
 Offspring + both parents 40.9 ± 15.6 39.4 ± 16.5 36.6 ± 14.3 660 
 Offspring only 32.9 ± 10.6 30.1 ± 11.0 28.7 ± 13.2 418 
Birth weight*     
n (%) 133 (69.3) 54 (28.1) 5 (2.6) 192 
 kg 3.73 ± 0.48 3.64 ± 0.52 3.62 ± 0.50  

Data are n, n (%), or means ± SD.

*

Birth weight (for offspring only) adjusted for gestational age, sex, year of birth, and maternal diabetes status; birth weight was not available for all subjects.

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