Frequency of diabetes and birth weight by −23 Hph1 genotype
. | A/A . | A/T . | T/T . | Total . |
---|---|---|---|---|
n (%) | ||||
Offspring + both parents | 458 (69.4) | 179 (27.2) | 23 (3.5) | 660 |
Offspring only | 293 (70.1) | 113 (27.0) | 12 (2.9) | 418 |
Sex (M/F) | ||||
Offspring + both parents | 212/245 | 72/117 | 13/10 | 660 |
Offspring only | 126/167 | 45/68 | 7/5 | 418 |
Number with diabetes (%) | ||||
Offspring + both parents | 255 (55.6) | 115 (64.3) | 16 (69.6) | 386 |
Offspring only | 140 (47.8) | 59 (52.2) | 6 (50) | 205 |
Age of diabetes onset (years) | ||||
Offspring + both parents | 33.7 ± 11.8 | 33.3 ± 12.1 | 31.4 ± 8.3 | 386 |
Offspring only | 28.1 ± 9.1 | 26.9 ± 9.8 | 29.1 ± 9.8 | 205 |
Age at last exam (years) | ||||
Offspring + both parents | 40.9 ± 15.6 | 39.4 ± 16.5 | 36.6 ± 14.3 | 660 |
Offspring only | 32.9 ± 10.6 | 30.1 ± 11.0 | 28.7 ± 13.2 | 418 |
Birth weight* | ||||
n (%) | 133 (69.3) | 54 (28.1) | 5 (2.6) | 192 |
kg | 3.73 ± 0.48 | 3.64 ± 0.52 | 3.62 ± 0.50 |
. | A/A . | A/T . | T/T . | Total . |
---|---|---|---|---|
n (%) | ||||
Offspring + both parents | 458 (69.4) | 179 (27.2) | 23 (3.5) | 660 |
Offspring only | 293 (70.1) | 113 (27.0) | 12 (2.9) | 418 |
Sex (M/F) | ||||
Offspring + both parents | 212/245 | 72/117 | 13/10 | 660 |
Offspring only | 126/167 | 45/68 | 7/5 | 418 |
Number with diabetes (%) | ||||
Offspring + both parents | 255 (55.6) | 115 (64.3) | 16 (69.6) | 386 |
Offspring only | 140 (47.8) | 59 (52.2) | 6 (50) | 205 |
Age of diabetes onset (years) | ||||
Offspring + both parents | 33.7 ± 11.8 | 33.3 ± 12.1 | 31.4 ± 8.3 | 386 |
Offspring only | 28.1 ± 9.1 | 26.9 ± 9.8 | 29.1 ± 9.8 | 205 |
Age at last exam (years) | ||||
Offspring + both parents | 40.9 ± 15.6 | 39.4 ± 16.5 | 36.6 ± 14.3 | 660 |
Offspring only | 32.9 ± 10.6 | 30.1 ± 11.0 | 28.7 ± 13.2 | 418 |
Birth weight* | ||||
n (%) | 133 (69.3) | 54 (28.1) | 5 (2.6) | 192 |
kg | 3.73 ± 0.48 | 3.64 ± 0.52 | 3.62 ± 0.50 |
Data are n, n (%), or means ± SD.
Birth weight (for offspring only) adjusted for gestational age, sex, year of birth, and maternal diabetes status; birth weight was not available for all subjects.