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Table 2—

Clinical features and biochemical characteristics of the patients with different renal pathologieslegend

Clinical featuresGroup I: DGS onlyGroup II: DGS with NDNGroup III: NDN onlyP
n (%) 24 (35) 13 (19) 31 (46)  
M/F (n14/10 9/4 15/16 NS 
Age (years) 49.0 ± 11.6 48.7 ± 16.5 48.4 ± 13.5 NS 
Duration of diabetes prior to biopsy (months) 99.6 ± 69.7* 94.3 ± 78.7 52.6 ± 42.0 0.031 
Proteinuria at biopsy (median g/day) 2.10 2.50 1.90 NS 
Proteinuria ≥2 g at biopsy (%) 58.3 69.2 48.4 NS 
Proteinuria at follow-up (median g/day) 2.60 2.30 2.00 NS 
SCr at biopsy (μmol/l) 167 ± 105* 176 ± 79 140 ± 44 0.004 
SCr ≥120 μmol/l at biopsy (%) 54.2* 53.8 19.4 0.014 
Hypertension at biopsy (%) 87.5 92.3 64.5 0.048 
Blood pressure at follow-up (mmHg) 101 ± 11 111 ± 13 101 ± 10 0.037 
On ACE inhibitor (%) 60.9 84.6 63.3 NS 
BMI at biopsy (kg/m224.9 ± 3.9 25.4 ± 9.5 25.6 ± 6.1 NS 
HbA1c at follow-up (%) 7.47 ± 2.59 8.99 ± 1.94 7.47 ± 2.19 NS 
Prevalence on insulin (%) 50         39 16 0.02 
Total cholesterol at biopsy (mmol/l) 5.9 ± 1.3 5.3 ± 1.6 5.7 ± 2.1 NS 
Retinopathy at biopsy (%) 70.8* 38.5 9.7 0.000 
Hematuria at biopsy (%) 35.3 23.1 35.5 NS 
Clinical featuresGroup I: DGS onlyGroup II: DGS with NDNGroup III: NDN onlyP
n (%) 24 (35) 13 (19) 31 (46)  
M/F (n14/10 9/4 15/16 NS 
Age (years) 49.0 ± 11.6 48.7 ± 16.5 48.4 ± 13.5 NS 
Duration of diabetes prior to biopsy (months) 99.6 ± 69.7* 94.3 ± 78.7 52.6 ± 42.0 0.031 
Proteinuria at biopsy (median g/day) 2.10 2.50 1.90 NS 
Proteinuria ≥2 g at biopsy (%) 58.3 69.2 48.4 NS 
Proteinuria at follow-up (median g/day) 2.60 2.30 2.00 NS 
SCr at biopsy (μmol/l) 167 ± 105* 176 ± 79 140 ± 44 0.004 
SCr ≥120 μmol/l at biopsy (%) 54.2* 53.8 19.4 0.014 
Hypertension at biopsy (%) 87.5 92.3 64.5 0.048 
Blood pressure at follow-up (mmHg) 101 ± 11 111 ± 13 101 ± 10 0.037 
On ACE inhibitor (%) 60.9 84.6 63.3 NS 
BMI at biopsy (kg/m224.9 ± 3.9 25.4 ± 9.5 25.6 ± 6.1 NS 
HbA1c at follow-up (%) 7.47 ± 2.59 8.99 ± 1.94 7.47 ± 2.19 NS 
Prevalence on insulin (%) 50         39 16 0.02 
Total cholesterol at biopsy (mmol/l) 5.9 ± 1.3 5.3 ± 1.6 5.7 ± 2.1 NS 
Retinopathy at biopsy (%) 70.8* 38.5 9.7 0.000 
Hematuria at biopsy (%) 35.3 23.1 35.5 NS 
legend

Data are means ± SD, unless otherwise indicated.

*

Significant difference between groups I and III;

significant difference between groups II and III;

significant difference between groups I and II. NS, not significant.

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