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Table 1—

Clinical and metabolic parameters measured at the end of each 4-week alcohol period

Baseline alcohol intakeLow alcohol intakeUsual alcohol intake
Alcohol intake (g/day) 68.1 ± 4.6 7.9 ± 1.6* 72.4 ± 5.0 
Weight (kg) 84.1 ± 1.6 83.0 ± 1.5 83.9 ± 1.6 
HDLC (mmol/l) 1.35 ± 0.08 1.13 ± 0.07* 1.36 ± 0.07 
γ-GT (units/l) 24.4 (20.0–29.8) 18.6 (15.5–22.2)* 24.4 (19.7–30.2) 
Fasting glucose (mmol/l) 5.1 ± 0.1 5.0 ± 0.1 5.0 ± 0.1 
Fasting insulin (pmol/l) 36 ± 4 34 ± 6 33 ± 3 
ISI (ml/kg · min−1 · pmol/l) × 103 17.7 (13.3–23.7) 18.8 (13.1–26.9) 20.2 (13.8–29.5) 
HOMA score 1.05 (0.83–1.33) 0.93 (0.69–1.24) 0.86 (0.58–1.27) 
Gss (mmol/l) 5.2 ± 0.1 5.1 ± 0.1 5.0 ± 0.1 
Iss (pmol/l) 242 ± 15 244 ± 23 230 ± 22 
Fructosamine (μmol/l) 219 ± 4 227 ± 5 223 ± 5 
Baseline alcohol intakeLow alcohol intakeUsual alcohol intake
Alcohol intake (g/day) 68.1 ± 4.6 7.9 ± 1.6* 72.4 ± 5.0 
Weight (kg) 84.1 ± 1.6 83.0 ± 1.5 83.9 ± 1.6 
HDLC (mmol/l) 1.35 ± 0.08 1.13 ± 0.07* 1.36 ± 0.07 
γ-GT (units/l) 24.4 (20.0–29.8) 18.6 (15.5–22.2)* 24.4 (19.7–30.2) 
Fasting glucose (mmol/l) 5.1 ± 0.1 5.0 ± 0.1 5.0 ± 0.1 
Fasting insulin (pmol/l) 36 ± 4 34 ± 6 33 ± 3 
ISI (ml/kg · min−1 · pmol/l) × 103 17.7 (13.3–23.7) 18.8 (13.1–26.9) 20.2 (13.8–29.5) 
HOMA score 1.05 (0.83–1.33) 0.93 (0.69–1.24) 0.86 (0.58–1.27) 
Gss (mmol/l) 5.2 ± 0.1 5.1 ± 0.1 5.0 ± 0.1 
Iss (pmol/l) 242 ± 15 244 ± 23 230 ± 22 
Fructosamine (μmol/l) 219 ± 4 227 ± 5 223 ± 5 

Data are means ± SE and geometric mean (95% CI). Significant differences

*

P < 0.001,

P < 0.05 from usual alcohol intake (paired t test low alcohol intake versus usual alcohol intake). n = 16 except for ISI, Gss, and Iss, where n = 12.

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