Clinical and metabolic parameters measured at the end of each 4-week alcohol period
| . | Baseline alcohol intake . | Low alcohol intake . | Usual alcohol intake . |
|---|---|---|---|
| Alcohol intake (g/day) | 68.1 ± 4.6 | 7.9 ± 1.6* | 72.4 ± 5.0 |
| Weight (kg) | 84.1 ± 1.6 | 83.0 ± 1.5† | 83.9 ± 1.6 |
| HDLC (mmol/l) | 1.35 ± 0.08 | 1.13 ± 0.07* | 1.36 ± 0.07 |
| γ-GT (units/l) | 24.4 (20.0–29.8) | 18.6 (15.5–22.2)* | 24.4 (19.7–30.2) |
| Fasting glucose (mmol/l) | 5.1 ± 0.1 | 5.0 ± 0.1 | 5.0 ± 0.1 |
| Fasting insulin (pmol/l) | 36 ± 4 | 34 ± 6 | 33 ± 3 |
| ISI (ml/kg · min−1 · pmol/l) × 103 | 17.7 (13.3–23.7) | 18.8 (13.1–26.9) | 20.2 (13.8–29.5) |
| HOMA score | 1.05 (0.83–1.33) | 0.93 (0.69–1.24) | 0.86 (0.58–1.27) |
| Gss (mmol/l) | 5.2 ± 0.1 | 5.1 ± 0.1 | 5.0 ± 0.1 |
| Iss (pmol/l) | 242 ± 15 | 244 ± 23 | 230 ± 22 |
| Fructosamine (μmol/l) | 219 ± 4 | 227 ± 5 | 223 ± 5 |
| . | Baseline alcohol intake . | Low alcohol intake . | Usual alcohol intake . |
|---|---|---|---|
| Alcohol intake (g/day) | 68.1 ± 4.6 | 7.9 ± 1.6* | 72.4 ± 5.0 |
| Weight (kg) | 84.1 ± 1.6 | 83.0 ± 1.5† | 83.9 ± 1.6 |
| HDLC (mmol/l) | 1.35 ± 0.08 | 1.13 ± 0.07* | 1.36 ± 0.07 |
| γ-GT (units/l) | 24.4 (20.0–29.8) | 18.6 (15.5–22.2)* | 24.4 (19.7–30.2) |
| Fasting glucose (mmol/l) | 5.1 ± 0.1 | 5.0 ± 0.1 | 5.0 ± 0.1 |
| Fasting insulin (pmol/l) | 36 ± 4 | 34 ± 6 | 33 ± 3 |
| ISI (ml/kg · min−1 · pmol/l) × 103 | 17.7 (13.3–23.7) | 18.8 (13.1–26.9) | 20.2 (13.8–29.5) |
| HOMA score | 1.05 (0.83–1.33) | 0.93 (0.69–1.24) | 0.86 (0.58–1.27) |
| Gss (mmol/l) | 5.2 ± 0.1 | 5.1 ± 0.1 | 5.0 ± 0.1 |
| Iss (pmol/l) | 242 ± 15 | 244 ± 23 | 230 ± 22 |
| Fructosamine (μmol/l) | 219 ± 4 | 227 ± 5 | 223 ± 5 |
Data are means ± SE and geometric mean (95% CI). Significant differences
P < 0.001,
P < 0.05 from usual alcohol intake (paired t test low alcohol intake versus usual alcohol intake). n = 16 except for ISI, Gss, and Iss, where n = 12.