Skip to Main Content
Table 4—

Correlations between concurrent HbA1c and the standard lipid profile, NMR-determined lipoprotein profile, apolipoprotein levels in sera, and response to in vitro oxidation of LDL from women and men in the 1997–1999 DCCT/EDIC cohort

Women (n = 428)
Men (n = 540)
rPr*P1rPr*P1
Conventional total cholesterol (mg/dl) 0.19 <0.001 0.10 0.09 0.17 <0.0001 0.18 <0.001 
Conventional total triglyceride (mg/dl) 0.21 <0.0001 0.16 <0.05 0.14 <0.005 0.18 <0.001 
Conventional LDL cholesterol (mg/dl) 0.18 <0.001 0.11 0.08 0.15 <0.005 0.17 <0.005 
Conventional HDL cholesterol (mg/dl) −0.08 0.10 −0.06 NS −0.05 NS −0.09 0.09 
NMR Large VLDL subclass (TG, mg/dl) 0.14 <0.005 0.11 0.07 0.08 0.06 0.09 NS 
NMR Medium VLDL subclass (TG, mg/dl) 0.12 <0.05 0.06 NS 0.10 <0.05 0.10 0.06 
NMR Small VLDL subclass (TG, mg/dl) 0.22 <0.0001 0.21 <0.001 0.14 <0.005 0.13 <0.05 
NMR IDL subclass (cholesterol, mg/dl) 0.03 NS 0.01 NS 0.00 NS −0.04 NS 
NMR L3 subclass (cholesterol, mg/dl) 0.05 NS −0.02 NS −0.03 NS −0.01 NS 
NMR L2 subclass (cholesterol, mg/dl) 0.12 <0.05 0.12 0.05 0.06 NS 0.08 NS 
NMR L1 subclass (cholesterol, mg/dl) 0.04 NS 0.06 NS 0.16 <0.001 0.13 <0.05 
NMR Large HDL subclass (cholesterol, mg/dl) −0.09 0.08 −0.09 NS −0.08 NS −0.09 NS 
NMR Small HDL subclass (cholesterol, mg/dl) 0.15 <0.005 0.15 <0.05 0.09 <0.05 0.05 NS 
NMR VLDL particle size (nm) −0.04 NS 0.00 NS 0.05 NS 0.06 NS 
NMR LDL particle size (nm) −0.03 NS −0.07 NS −0.12 <0.005 −0.09 0.10 
NMR HDL particle size (nm) −0.22 <0.0001 −0.23 <0.001 −0.16 <0.001 −0.14 <0.05 
NMR LDL particle concentration (nmol/l) 0.20 <0.0001 0.17 <0.01 0.24 <0.0001 0.23 <0.0001 
ApoB (mg/dl) 0.26 <0.0001 0.22 <0.001 0.19 <0.0001 0.22 <0.0001 
Women (n = 428)
Men (n = 540)
rPr*P1rPr*P1
Conventional total cholesterol (mg/dl) 0.19 <0.001 0.10 0.09 0.17 <0.0001 0.18 <0.001 
Conventional total triglyceride (mg/dl) 0.21 <0.0001 0.16 <0.05 0.14 <0.005 0.18 <0.001 
Conventional LDL cholesterol (mg/dl) 0.18 <0.001 0.11 0.08 0.15 <0.005 0.17 <0.005 
Conventional HDL cholesterol (mg/dl) −0.08 0.10 −0.06 NS −0.05 NS −0.09 0.09 
NMR Large VLDL subclass (TG, mg/dl) 0.14 <0.005 0.11 0.07 0.08 0.06 0.09 NS 
NMR Medium VLDL subclass (TG, mg/dl) 0.12 <0.05 0.06 NS 0.10 <0.05 0.10 0.06 
NMR Small VLDL subclass (TG, mg/dl) 0.22 <0.0001 0.21 <0.001 0.14 <0.005 0.13 <0.05 
NMR IDL subclass (cholesterol, mg/dl) 0.03 NS 0.01 NS 0.00 NS −0.04 NS 
NMR L3 subclass (cholesterol, mg/dl) 0.05 NS −0.02 NS −0.03 NS −0.01 NS 
NMR L2 subclass (cholesterol, mg/dl) 0.12 <0.05 0.12 0.05 0.06 NS 0.08 NS 
NMR L1 subclass (cholesterol, mg/dl) 0.04 NS 0.06 NS 0.16 <0.001 0.13 <0.05 
NMR Large HDL subclass (cholesterol, mg/dl) −0.09 0.08 −0.09 NS −0.08 NS −0.09 NS 
NMR Small HDL subclass (cholesterol, mg/dl) 0.15 <0.005 0.15 <0.05 0.09 <0.05 0.05 NS 
NMR VLDL particle size (nm) −0.04 NS 0.00 NS 0.05 NS 0.06 NS 
NMR LDL particle size (nm) −0.03 NS −0.07 NS −0.12 <0.005 −0.09 0.10 
NMR HDL particle size (nm) −0.22 <0.0001 −0.23 <0.001 −0.16 <0.001 −0.14 <0.05 
NMR LDL particle concentration (nmol/l) 0.20 <0.0001 0.17 <0.01 0.24 <0.0001 0.23 <0.0001 
ApoB (mg/dl) 0.26 <0.0001 0.22 <0.001 0.19 <0.0001 0.22 <0.0001 
*

Partial correlation coefficient. P univariate analysis. P1 adjusted for age, duration of diabetes, hypertension, BMI, WHR, AER, and DCCT randomization group.

Close Modal

or Create an Account

Close Modal
Close Modal