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Table 2—

Clinical, metabolic, and immunological features at diabetes onset in the population-based cohort of incident cases of type 1 diabetes in the province of Turin, Italy, from 1984 to 2000

Age-group (years)Glucose (mmol/l)KetonuriaHospital admissionFasting C-peptide (nmol/l)Stimulated C-peptide (nmol/l)ICA+GADA+IA2+
n 842 769 947 575 180 262 254 183 
0–4 24.9 ± 8.3 90 (96.8) 102 (99.0) 0.07 0.14 11 (64.7) 10 (58.8) 8 (66.7) 
5–9 22.9 ± 11.3 146 (90.7) 174 (98.9) 0.08 0.19 33 (64.7) 30 (58.82) 31 (81.6) 
10–14 21.9 ± 8.6 179 (93.7) 200 (88.5) 0.15 0.27 28 (59.6) 26 (54.2) 21 (65.6) 
15–19 24.1 ± 10.7 95 (88.0) 114 (74.5) 0.21 0.48 23 (53.5) 27 (64.3) 11 (44.0) 
20–24 23.4 ± 10.6 96 (90.6) 94 (61.4) 0.23 0.48 30 (47.6) 41 (71.9) 18 (51.4) 
25–29 21.1 ± 10.2 93 (84.6) 83 (61.0) 0.24 0.43 19 (46.3) 26 (66.7) 10 (50.0) 
    P 0.04* 0.03 <0.0001 <0.0001* <0.0001* 0.34 0.50 0.003 
0–14 22.9 ± 9.6 415 (93.3) 476 (94.3) 0.10 0.21 72 (62.6) 66 (56.9) 60 (73.2) 
15–29 22.8 ± 10.6 284 (87.6) 291 (65.8) 0.23 0.47 72 (49.0) 94 (68.1) 39 (48.7) 
    P 0.89 0.008 <0.0001 <0.0001 <0.001 0.028 0.06 0.001 
Age-group (years)Glucose (mmol/l)KetonuriaHospital admissionFasting C-peptide (nmol/l)Stimulated C-peptide (nmol/l)ICA+GADA+IA2+
n 842 769 947 575 180 262 254 183 
0–4 24.9 ± 8.3 90 (96.8) 102 (99.0) 0.07 0.14 11 (64.7) 10 (58.8) 8 (66.7) 
5–9 22.9 ± 11.3 146 (90.7) 174 (98.9) 0.08 0.19 33 (64.7) 30 (58.82) 31 (81.6) 
10–14 21.9 ± 8.6 179 (93.7) 200 (88.5) 0.15 0.27 28 (59.6) 26 (54.2) 21 (65.6) 
15–19 24.1 ± 10.7 95 (88.0) 114 (74.5) 0.21 0.48 23 (53.5) 27 (64.3) 11 (44.0) 
20–24 23.4 ± 10.6 96 (90.6) 94 (61.4) 0.23 0.48 30 (47.6) 41 (71.9) 18 (51.4) 
25–29 21.1 ± 10.2 93 (84.6) 83 (61.0) 0.24 0.43 19 (46.3) 26 (66.7) 10 (50.0) 
    P 0.04* 0.03 <0.0001 <0.0001* <0.0001* 0.34 0.50 0.003 
0–14 22.9 ± 9.6 415 (93.3) 476 (94.3) 0.10 0.21 72 (62.6) 66 (56.9) 60 (73.2) 
15–29 22.8 ± 10.6 284 (87.6) 291 (65.8) 0.23 0.47 72 (49.0) 94 (68.1) 39 (48.7) 
    P 0.89 0.008 <0.0001 <0.0001 <0.001 0.028 0.06 0.001 

Data are means ± SD, geometric means, or n (%).

*

Based on linear regression analysis;

based on Student’s t test.

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