American Diabetes Association

Table 4

Relative influence of modifiable and nonmodifiable risk factors on the association between type 2 diabetes and dementia risk

Alzheimer disease	RI, %	Vascular dementia	RI, %	Nonvascular dementia	RI, %
Age	74.5	Age	47.84	Age	81.71
BMI	13.7	Diastolic blood pressure	13.46	BMI	5.48
Systolic blood pressure	4.91	Systolic blood pressure	7.84	Type 2 diabetes duration	2.32
Type 2 diabetes duration	1.45	Type 2 diabetes duration	7.47	Diastolic blood pressure	1.70
Income	1.30	CVD	5.76	Glomerular filtration rate	1.60
Glomerular filtration rate	1.04	BMI	5.07	Systolic blood pressure	1.51
HDL	1.22	Glomerular filtration rate	4.52	CVD	1.49
LDL	0.86	LDL	2.44	HbA_1c	1.06
Diastolic blood pressure	0.49	HbA_1c	1.78	Income	1.00
HbA_1c	0.32	Income	0.95	LDL	0.54
Education	0.23	Macroalbuminuria	0.94	HDL	0.38
Microalbuminuria	0.10	HDL	0.77	Macroalbuminuria	0.35
Blood pressure medication	0.05	Male sex	0.62	Lipid medication	0.34
Male sex	0.02	Microalbuminuria	0.28	Blood pressure medication	0.21
Smoking	0.02	Smoking	0.18	Microalbuminuria	0.15
Lipid medication	0.002	Lipid medication	0.08	Education	0.09
Macroalbuminuria	0.004	Education	0.01	Smoking	0.05

Alzheimer disease	RI, %	Vascular dementia	RI, %	Nonvascular dementia	RI, %
Age	74.5	Age	47.84	Age	81.71
BMI	13.7	Diastolic blood pressure	13.46	BMI	5.48
Systolic blood pressure	4.91	Systolic blood pressure	7.84	Type 2 diabetes duration	2.32
Type 2 diabetes duration	1.45	Type 2 diabetes duration	7.47	Diastolic blood pressure	1.70
Income	1.30	CVD	5.76	Glomerular filtration rate	1.60
Glomerular filtration rate	1.04	BMI	5.07	Systolic blood pressure	1.51
HDL	1.22	Glomerular filtration rate	4.52	CVD	1.49
LDL	0.86	LDL	2.44	HbA_1c	1.06
Diastolic blood pressure	0.49	HbA_1c	1.78	Income	1.00
HbA_1c	0.32	Income	0.95	LDL	0.54
Education	0.23	Macroalbuminuria	0.94	HDL	0.38
Microalbuminuria	0.10	HDL	0.77	Macroalbuminuria	0.35
Blood pressure medication	0.05	Male sex	0.62	Lipid medication	0.34
Male sex	0.02	Microalbuminuria	0.28	Blood pressure medication	0.21
Smoking	0.02	Smoking	0.18	Microalbuminuria	0.15
Lipid medication	0.002	Lipid medication	0.08	Education	0.09
Macroalbuminuria	0.004	Education	0.01	Smoking	0.05

Analyses were mutually adjusted for all covariates. RI, relative influence.