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TABLE 2.3

Criteria for Screening for Diabetes or Prediabetes in Asymptomatic Adults

1. Testing should be considered in adults with overweight or obesity (BMI ≥25 kg/m2 or ≥23 kg/m2 in Asian American individuals) who have one or more of the following risk factors: 
 • First-degree relative with diabetes 
 • High-risk race/ethnicity (e.g., African American, Latino, Native American, Asian American, Pacific Islander) 
 • History of CVD 
 • Hypertension (≥140/90 mmHg or on therapy for hypertension) 
 • HDL cholesterol level <35 mg/dL (0.90 mmol/L) and/or a triglyceride level >250 mg/dL (2.82 mmol/L) 
 • Individuals with polycystic ovary syndrome 
 • Physical inactivity 
 • Other clinical conditions associated with insulin resistance (e.g., severe obesity, acanthosis nigricans) 
2. People with prediabetes (A1C ≥5.7% [39 mmol/mol], IGT, or IFG) should be tested yearly. 
3. People who were diagnosed with GDM should have lifelong testing at least every 3 years. 
4. For all other people, testing should begin at age 35 years. 
5. If results are normal, testing should be repeated at a minimum of 3-year intervals, with consideration of more frequent testing depending on initial results and risk status. 
6. People with HIV. 
1. Testing should be considered in adults with overweight or obesity (BMI ≥25 kg/m2 or ≥23 kg/m2 in Asian American individuals) who have one or more of the following risk factors: 
 • First-degree relative with diabetes 
 • High-risk race/ethnicity (e.g., African American, Latino, Native American, Asian American, Pacific Islander) 
 • History of CVD 
 • Hypertension (≥140/90 mmHg or on therapy for hypertension) 
 • HDL cholesterol level <35 mg/dL (0.90 mmol/L) and/or a triglyceride level >250 mg/dL (2.82 mmol/L) 
 • Individuals with polycystic ovary syndrome 
 • Physical inactivity 
 • Other clinical conditions associated with insulin resistance (e.g., severe obesity, acanthosis nigricans) 
2. People with prediabetes (A1C ≥5.7% [39 mmol/mol], IGT, or IFG) should be tested yearly. 
3. People who were diagnosed with GDM should have lifelong testing at least every 3 years. 
4. For all other people, testing should begin at age 35 years. 
5. If results are normal, testing should be repeated at a minimum of 3-year intervals, with consideration of more frequent testing depending on initial results and risk status. 
6. People with HIV. 

IFG, impaired fasting glucose; IGT, impaired glucose tolerance.

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