Stages and prognosis of CKD based on albuminuria and GFR from the KDIGO (Kidney Disease: Improving Global Outcomes) 2012 clinical practice guideline (109). The GFR and albuminuria grid depicts the risk of progression, morbidity, and mortality by color, from best to worst. Green indicates low risk (if no other markers of kidney disease and no CKD), yellow indicates moderately increased risk, orange indicates high risk, and red indicates very high risk. Reprinted with permission from Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. Kidney Int Suppl 2013;3:1–150.